AtropineĪtropine is injected intramuscularly (into the thigh) in 2mg doses every 3-8 minutes. With no acetylcholine reaching or binding to the receptors it is unimportant that the acetylcholinesterase is being destroyed by the VX Gas. VX stimulates the muscles, so as atropine ceases the constant stimulation it acts as an antidote. This prevents acetylcholine from binding to the receptors and sending impulses to the muscles. Atropine acts by competitivly binding to the muscarinic (acetylcholine) receptors in the muscles. Unfortunately, none of these three antidotes are useful in a widespread situation as they are all slow acting and require the assistance of a second party.Ītropine is a nerve gas itself, but is a suitable antidote to VX gas. Despite sounding old fashioned, if VX in liquid form can be wiped off the skin quickly enough, victims have a chance of survival, particularly if they are taken to hospital and treated immediately. Pralidoxine is infused intravenously (1.5mg over 15 minutes) and continually repeated after 10 minutes until muscle control returns. Pyridostigmine bromide enhances the effects of other antidotes by competitively inhibiting (binding to) acetylcholinesterase, and is taken in tablet form.
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